Newswire (Published: Thursday, June 4, 2020, Received: Thursday, June 4, 2020, 4:19:27 PM CDT)

Word Count: 480

2020 JUN 04 (NewsRx) -- By a News Reporter-Staff News Editor at Disease Prevention Daily -- Investigators publish new report on Oncology - Prostate Cancer. According to news reporting originating in Chicago, Illinois, by NewsRx journalists, research stated, “Treatment decisions for elderly men with prostate cancer are complicated by the intersection of competing risks of cancer, potential complications of treatment, and individual patients’ comorbidities. To perform a systematic review of data guiding the assessment of elderly prostate cancer patients that addresses the risk from cancer and treatment, and to discuss a patient-centered approach to incorporating these factors into decision making.”

The news reporters obtained a quote from the research from Northwestern University, “Evidence was gathered via a systematic review of the current literature. The search strategy used the terms prostate cancer, elderly, geriatric, >75 yr of age, risk assessment, and treatment in several combinations, and was limited to phase II clinical trials published between January 2008 and November 2018. Additional supporting literature for the discussion was pulled by hand search. The benefits of treatment identified for systemic therapies commonly used to treat men with prostate in general extend to elderly patients. Evidence supports a multifaceted assessment of the risks of cancer and aging, and an understanding of the side effects of treatment to optimally guide therapeutic decision making for elderly patients. There is little evidence defining a geriatric risk stratification system specific to prostate cancer, and recommendations are predominantly based on adapted geriatric oncology approaches and expert consensus. The care of elderly men with prostate cancer should incorporate a review of cancer risk, an assessment of aging, and an understanding of the effects of treatment to provide the patient with thorough and personalized guidance for treatment decisions. Future studies of elderly men with prostate cancer can define and validate ideal risk stratification methods as well as management approaches that may be distinct from those for younger populations.”

According to the news reporters, the research concluded: “Treatment decisions for elderly men with prostate cancer require consideration of the risk posed by the cancer coupled with an understanding of the patient’s general health status.”

For more information on this research see: Risk Assessment and Considerations for Proper Management of Elderly Men with Advanced Prostate Cancer: A Systematic Review. European Urology Oncology, 2020;():.

Our news correspondents report that additional information may be obtained by contacting A.B. Weiner, Northwestern University, Chicago, IL, United States. Additional authors for this research include J.W. Shevach, R.N. Kasimer, C.H. Miller and A.K Morgans.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.euo.2020.03.006. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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