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  Findings from Department of Radiation Oncology Yields New Data on Prostate Cancer  

Cancer Weekly (Published: Tuesday, April 15, 2014, Received: Thursday, April 10, 2014, 3:27:27 AM CDT)
Word Count: 432

By a News Reporter-Staff News Editor at Cancer Weekly -- A new study on Oncology is now available. According to news reporting originating in Athens, Greece, by NewsRx journalists, research stated, "The purpose of this study was to compare the planning approaches used in two treatment planning systems (TPS) provided by Elekta for VMAT treatments. Ten prostate patients were studied retrospectively."

The news reporters obtained a quote from the research from the Department of Radiation Oncology, "Plan comparison was performed in terms of delivery efficiency and accuracy, as well as in terms of target coverage and critical organ protection by utilizing physical and radiobiological indices. These include: DVH (dose volume histogram) values, CI (conformity index), HI(%) (homogeneity index) and TCP (tumor control probability) for target coverage; mean doses, DVH values, dose to the normal non-target tissue, NTCP (normal tissue complication probability) and GI (gradient index) for critical organ sparing; MU/fraction and treatment time for delivery efficiency. The comparisons were performed using the two-sided Wilcoxon matched-pair signed rank test. Plans generated using the anatomy-based approach in ERGO++ and fluence-based approach in Monaco were found similar in terms of target coverage and TCP values, as well as in terms of rectum protection and corresponding NTCP values. The former exhibited increased delivery efficiency (comparable to that of 3D conformal radiotherapy) due to the relatively larger segments used."

According to the news reporters, the research concluded: "On the other hand advantages of the fluence-based approach in Monaco include increased conformity, better target dose homogeneity and higher dose gradient (lower dose to normal non-target-tissue) mainly due to the higher degree of modulation offered by the fluence-based approach, while the Monte Carlo algorithm used for dose calculation provides plans with increased accuracy despite the relatively small segments used."

For more information on this research see: Anatomy- vs. fluence-based planning for prostate cancer treatments using VMAT. Physica Medica-European Journal of Medical Physics, 2014;30(2):202-208. Physica Medica-European Journal of Medical Physics can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England (see also Oncology).

Our news correspondents report that additional information may be obtained by contacting M. Andreou, Hygeia Hosp, Dept. of Radiat Oncol, Athens, Greece. Additional authors for this research include P. Karaiskos, S. Kordolaimi, E. Koutsouveli, P. Sandilos, P. Dimitriou, C. Dardoufas and E. Georgiou.

Keywords for this news article include: Athens, Greece, Europe, Oncology, Radiotherapy, Prostate Cancer, Prostatic Neoplasms

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