Hot SHEET 2015

Made possible by charitable contributions from Astellas / Medivation, SanofiPints for Prostates, Genomic Health.

Our monthly newsletter, the Hot SHEET, highlights the latest in treatment strategies as well as emerging treatments. The Hot SHEET is distributed free at chapter support group meetings, and is available in PDF on the Us TOO web site.

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If you are unable to attend chapter meetings to get the latest issue or prefer an original copy, we can deliver the newsletter right to your home or office. Download and print a subscription order form or order online.

We thankfully acknowledge the following sponsors of the
11th Annual SEA Blue Chicago Prostate Cancer Walk & Run


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  • Active Surveillance Doesn't Impair QOL
  • ASCO Endorses AUA Guidelines on Adjuvant RT Following Prostatectomy
  • ADT Linked to Heart Deaths in Men with Prior History of Heart Disease
  • Obesity Increases the Risk of High-Grade Prostate Cancer
  • Photodynamic Diagnosis of Shed Prostate Cancer Cells in Voided Urine
  • Doc Moyad's "No Bogus Science" Column – Why Do Rabbits Have Perfect Vision?
  • Doctor Chodak's Bottom Line
  • Index of Articles Appearing in 2014 Hot SHEETS
  • Sexual Partners, Sexually Transmitted Infections & Prostate Cancer Risk
  • Two Prostate Cancer Tests 'Not Clinically Useful' Says NICE
  • Surveillance May Be Safest Option for Low- Risk Prostate Cancer
  • Lower Death Rates in Men with Prostate Cancer Who Exercise
  • Diethylstilbestrol (DES) for CRPC
  • CyberKnife for Isolated Nodal Recurrence
  • Doc Moyad's "No Bogus Science" Column – "TV Shows Offering Wrong Health Advice"
  • New Us TOO Board Members
  • A Prospective Assessment of Patient Scar Satisfaction According to Type of RP
  • More Evidence of Harm from Selenium
  • Elucidating Immunological Mechanisms of PROSTVAC Cancer Immunotherapy
  • Doctor Chodak's Bottom Line
  • POM Loses Bid to Claim Health Benefits
  • MRI/Ultrasound Biopsy & High-Risk Disease
  • PDE5 Use & Risk of BCR after RP
  • Positive Surgical Margins & Mortality
  • Bone Complications from Long-Term ADT
  • Prostate Biopsies May Be More Accurate at Academic Centers
  • Doc Moyad's "No Bogus Science" Column – "Dietary Supplements and Jim Harbaugh"
  • Lap vs. Mini-Lap Robot-Assisted RP & Scars
  • Providing Clinicians & Patients with Actual Prognosis: Cancer vs. Non-Cancer Mortality
  • Duration of ADT before RT—How Long?
  • Docs 'Astonished' about PDE5 Drugs & BCR
  • Doctor Chodak's Bottom Line
  • Add Radiation to ADT for Localized PCa
  • Decline in PSA Screening & High-Risk PCa
  • Genomic Classifier Score & Risk/Benefits of Adjuvant Radiotherapy Post-Prostatectomy
  • Persistent Positive Prostate Biopsies after High-Dose Rate Brachytherapy for PCa
  • Radiographic Progression-Free Survival as a Response Biomarker for Abiraterone Therapy
  • Doc Moyad’s "No Bogus Science" Column – "Metformin, Cancer and Atherosclerosis"
  • Prostatectomy Impairs Sex for Both Partners
  • Non-Steroidal Antiandrogen vs. LHRH-A
  • Rate of Observation for PCa Increasing
  • Bavarian Nordic Vaccine Helps Prolong Life in Prostate Cancer Trial
  • Doctor Chodak's Bottom Line
  • New Data Revive Active Surveillance Debate
  • Abiraterone before Chemo Improves Survival
  • RT after Prostatectomy: Debate Over Timing
  • Enzalutamide Efficacy May Be Affected when Given after Abiraterone or Docetaxel
  • Diffusion of Docetaxel for Metastatic CRPC
  • Doc Moyad's "No Bogus Science" Column – "Start Low, Go Slow & Save Side Effects"
  • Higher Mortality in Men with Intermediate-Risk Prostate Cancer Managed by AS
  • Nadir Testosterone on ADT Predicts Survival
  • Infections Rising after Prostate Biopsies
  • Doctor Chodak's Bottom Line
  • Medical & Surgical Castration May Increase the Risk of Cardiovascular Events
  • Prostate Cancer Treatment with New Injectable Gel
  • Low Use of Adjuvant Radiotherapy after Radical Prostatectomy
  • Aspirin Does Not Reduce Mortality in Prostate Cancer
  • Updated Results form the Spanish Branch of the ERSPC Trial
  • New Tool for Guiding Therapy in Prostate Cancer Patients
  • Docetaxel, Prednisone with/without Lenalidomide in Metastatic CPRC
  • Doc Moyad's "No Bogus Science" "Adult Vaccines for Heart Disease?"
  • Does Obesity Explain the High Risk for Prostate Cancer in Black Men?
  • Normal Erection after Radical Prostatectomy is Rare
  • Doctor Chodak's Bottom Line
  • Urine Assay Shows Promise as Test for High-Grade Prostate Cancer
  • Multiparametric MRI Avoids Many Biopsies but Misses a Few Cancers
  • Chemo-ADT Combo Still Winning in Prostate Cancer
  • Statins May Slow Prostate Cancer Progression Following ADT
  • Best Evidence Yet that Ejaculation Reduces Prostate Cancer Risk
  • Doc Moyad's "No Bogus Science" "Ginseng & Cancer-Related Fatigue"
  • Prostate Tumors with Genetic Abnormalities May Respond to Olaparib
  • Androgen Deprivation Therapy May Lead to Cognitive Impairment
  • Timing of Androgen Deprivation ("TOAD") Phase III Trial
  • Doctor Chodak's Bottom Line
  • MRIUltrasound Fusion Prostate Biopsy Find More HighGrade Tumors
  • ‘Genuine Change’ in US Prostate Cancer Management
  • Active Surveillance May Be Safe After Prostate Tumor Upgrade
  • Occult T3 Vs. Clinical T3 Tumors & PostProstatectomy Survival
  • Abiraterone in ChemotherapyNaïve Elderly Men (≥75 years) with CRPC
  • Doc Moyad’s "No Bogus Science" "More Obese Americans in History"
  • PDE5I and Melanoma Risk
  • Predicting Unfavorable Prostate Cancer Before Active Surveillance
  • Study of Prostate Cancer in Medically Underserved
  • DNA Repair Kinase Identified as Key Driver of Metastasis
  • Adding Docetaxel to ADT Improves Survival in Metastatic Disease
  • Circumcised Men Might Have a Lower Risk of Prostate Cancer
  • Decrease in Prostate Cancer Testing following USPSTF Recommendation
  • External Beam Radiotherapy Defeats High-Risk Prostate Cancer
  • New Data on Prostate Cancer, Salvage Radiotherapy & Survival
  • Doc Moyad's "No Bogus Science" "Vitamin D & Prostate Cancer"
  • No Risk of Venous Thromboembolism Seen with Testosterone Therapy
  • Prostate Cancer Genetically Divided into Five Distinct Subtypes
  • Some Low-Risk Prostate Cancers Require Closer Scrutiny
  • Doctor Chodak's Bottom Line
  • Men with Unaggressive Tumors Unlikely to Die from Prostate Cancer
  • Nearly 70% of US Prostate Cancers Could Be Watched
  • FDA to 'Low T' Drug Makers: Prove It
  • Ibandronate Similar to Radiotherapy for Prostate Cancer Bone Pain
  • Couple-Base Interventions Following Prostate Cancer Treatment
  • Doc Moyad's "No Bogus Science" "Pomegranate Is Same As Placebo"/li>
  • PSMA Expression is Highly Homogeneous in Primary Prostate Cancer
  • How the 'Heat' in Chili Peppers May Help Kill Prostate Cancer Cells
  • Nerve Sparing RP & Continence
  • Continence & Early Catheter Removal
  • Drug-Like Compounds Promising
  • Geographic Variation in Treatment of Localized Prostate Cancer
  • Doctor Chodak's Bottom Line
  • Weak Evidence Favors Usage of Intermittent ADT for Advanced PCa
  • Fewer, Larger RT Doses Prove Effective for Prostate Cancer Patients
  • Study Raises Questions about ADT in Certain Prostate Cancer Cases
  • ED Induced by Prostate Biopsy Is Likely "Underestimated"
  • Doc Moyad's "No Bogus Science" "Italy = Coffee = Moyad Experience"
  • Mutation Predicts Poor Chemotherapy Outcome
  • Silicon and Bone Health
  • PCa Diagnoses Drop after USPSTF 'Don't Screen' Recommendation
  • Appropriateness of Prostate Cancer Imaging in VA Cancer Registry
  • Doctor Chodak's Bottom Line
  • Randomized Phase II Trial of Lycopene- Rich Tomato Extract in High-Grade PIN
  • Choline Kinase-a Expression in Prostate Tissue Is Prognostic of Prostate Cancer
  • T Levels Improve in Obese Men after a Common Weight Loss Surgery
  • Long-Term ADT Is Best for Locally Advanced Prostate Cancer
  • 24 months of ATT Improves Survival for Men with Post-Surgical Recurrence
  • FDA Approves First Focused Ultrasound System for Prostate Treatment
  • Five-Point Likert Scaling on MRI Predicts Clinically Significant PCa
  • MRI & Disease Reclassification During AS for Low-Risk Prostate Cancer
  • Doc Moyad's "No Bogus Science" PLCO Results and Daily Fiber Intake
  • DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
  • High-Grade Prostate Cancer Linked to Elevated Cardiovascular Risk
  • Benefit of Nexrutine for Prevention
  • Liquid Biopsy Assay May Predict Abiraterone Resistance in CRPC
  • Costs of Treating Low-Risk Prostate Cancer Analyzed
  • Doctor Chodak's Bottom Line