Newswire (Published: Tuesday, June 27, 2017, Received: Friday, June 23, 2017, 12:52:55 AM CDT)

Word Count: 483

New Findings from Deakin University in the Area of Prostate Cancer Described (Cognitive decline in prostate cancer patients undergoing ADT: a potential role for exercise training)

By a News Reporter-Staff News Editor at Cancer Weekly -- Data detailed on Oncology - Prostate Cancer have been presented. According to news reporting originating from Geelong, Australia, by NewsRx correspondents, research stated, "Androgen deprivation therapy (ADT) is an effective and widely prescribed treatment for prostate cancer (PCa), but it is associated with multiple treatment-induced adverse effects that impact on various musculoskeletal and cardiometabolic health outcomes. Emerging research has shown that ADT is also associated with cognitive impairment, which has been linked to a loss of independence, increased falls and fracture risk and greater use of medical services."

Our news editors obtained a quote from the research from Deakin University, "The aim of this review is to outline the evidence related to the effect of ADT use on cognitive function, and propose a role for exercise training as part of usual care to prevent and/ or manage cognitive impairments for PCa survivors on ADT. The following results have been obtained from this study. ADT has been shown to adversely affect specific cognitive domains, particularly verbal memory, visuomotor function, attention and executive function. However, current clinical guidelines do not recommend routine assessment of cognitive function in these men. No studies have examined whether exercise training can preserve or improve cognitive function in these men, but in healthy adults', multimodal exercise training incorporating aerobic training, progressive resistance training (PRT) and challenging motor control exercises have the potential to attenuate cognitive decline."

According to the news editors, the research concluded: "As treatment with ADT for men with PCa has been associated with a decline in cognition, it is recommended that cognitive function be routinely monitored in these men and that regular exercise training be prescribed to preserve (or improve) cognitive function. Assessment of cognition and individualised exercise training should be considered in the usual treatment plan of PCa patients receiving ADT."

For more information on this research see: Cognitive decline in prostate cancer patients undergoing ADT: a potential role for exercise training. Endocrine-Related Cancer, 2017;24(4):R145-R155. Endocrine-Related Cancer can be contacted at: Bioscientifica Ltd, Euro House, 22 Apex Court Woodlands, Bradley Stoke, Bristol BS32 4JT, England (see also Oncology - Prostate Cancer).

The news editors report that additional information may be obtained by contacting N.L. Mundell, Deakin University, Sch Exercise & Nutr Sci, Inst Phys Activ & Nutr, Geelong, Vic, Australia. Additional authors for this research include R.M. Daly, H. Macpherson and S.F. Fraser.

Keywords for this news article include: Geelong, Australia, Australia and New Zealand, Cancer, Article Review, Risk and Prevention, Prostatic Neoplasms, Prostate Cancer, Oncology, Deakin University.

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