Newswire (Published: Tuesday, June 27, 2017, Received: Thursday, June 22, 2017, 4:44:41 PM CDT)

Word Count: 427

By a News Reporter-Staff News Editor at Cancer Weekly -- A new study on Oncology - Prostate Cancer is now available. According to news reporting out of Cleveland, Ohio, by NewsRx editors, the research stated, "The present review describes recent changes in the histologic grading of prostatic adenocarcinoma and emerging data suggesting areas for further grade optimization. The grading of prostatic adenocarcinoma has evolved over time, and optimization for active surveillance management has been one major driving force."

Our news journalists obtained a quote from the research from Cleveland Clinic, "Recent changes include adoption of the Grade Group system, which stratifies patients into one of five prognostic groups. Although it provides clearer labels for patient understanding and defines a more homogenous low-risk group (i.e. Grade Group 1 of 5), emerging data suggest that further prognostic stratification may be achieved by incorporating other histologic findings. The impact of 'cribriform histology' and intraductal carcinoma as aggressive features of prostate cancer has gained significant recognition. Furthermore, quantifying the fraction of each individual Gleason pattern component may also add prognostic stratification. In addition to Gleason score and Grade Group, some institutions now identify and report high-risk histologic patterns (e.g. 'cribriform histology') and the percentage of Gleason pattern 4 on biopsies. While early in adoption, these additional features are being used to further stratify patients beyond the Grade Group system, particularly for patients with Grade Group 2 carcinomas. These histologic findings will likely be incorporated into future modifications of the grading system to further optimize patient stratification and ensure reporting consistency. The histologic evaluation of prostatic adenocarcinoma provides strong prognostic information for clinical management."

According to the news editors, the research concluded: "The recent Grade Group system offers many improvements, but further optimization based on specific histologic patterns may evolve."

For more information on this research see: The present and future of prostate cancer histopathology. Current Opinion In Urology, 2017;():. (Lippincott Williams and Wilkins - www.lww.com; Current Opinion In Urology - journals.lww.com/co-urology/pages/default.aspx)

Our news journalists report that additional information may be obtained by contacting J.K. McKenney, Dept. of Anatomic Pathology, Robert J Tomsich Pathology and Laboratory Medicine & Glickman Urology and Kidney Institutes, Cleveland Clinic, Cleveland, Ohio, United States (see also Oncology - Prostate Cancer).

Keywords for this news article include: Ohio, Oncology, Cleveland, Histology, Epidemiology, United States, Adenocarcinoma, Histopathology, Prostate Cancer, Prostatic Neoplasms, North and Central America.

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