Newswire (Published: Saturday, January 14, 2017, Received: Friday, January 6, 2017, 3:28:14 PM CST)

Word Count: 509

Findings from University of Oxford in Prostate Cancer Reported [Lifestyle factors and prostate-specific antigen (PSA) testing in UK Biobank: Implications for epidemiological research]

By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Oncology - Prostate Cancer. According to news originating from Oxford, United Kingdom, by NewsRx correspondents, research stated, "The central role of prostate-specific antigen (PSA) testing in the diagnosis of prostate cancer leads to the possibility that observational studies that report associations between risk factors and prostate cancer could be affected by detection bias. This study aims to investigate whether reported risk factors for prostate cancer are associated with PSA testing in a large middle-aged population-based cohort in the UK."

Our news journalists obtained a quote from the research from the University of Oxford, "The cross-sectional association between a wide range of sociodemographic, lifestyle, dietary and health characteristics with PSA testing was examined in 212,039 men aged 40-69 years in UK Biobank. A total of 62,022 (29%) men reported they had ever had a PSA test. A wide range of factors was associated with a higher likelihood of PSA testing including age, height, education level, family history of prostate cancer, black ethnic origin, not being in paid/self-employment, living with a wife or partner, having had a vasectomy, being diagnosed with cancer or hypertension and having a high dietary intake of cereal, cooked and salad/raw vegetables, fresh fruit and tea. Conversely, socioeconomic deprivation, Asian ethnic origin, current smoking, low alcohol intake, high body-mass index, high coffee consumption and being diagnosed with diabetes, heart disease or stroke were associated with a lower likelihood of PSA testing."

According to the news editors, the research concluded: "A variety of sociodemographic, lifestyle and health-related characteristics are associated with PSA testing, suggesting that observed associations of some of these traits with risk for prostate cancer in epidemiological studies may be, at least partially, due to detection bias."

For more information on this research see: Lifestyle factors and prostate-specific antigen (PSA) testing in UK Biobank: Implications for epidemiological research. Cancer Epidemiology, 2016;45():40-46. Cancer Epidemiology can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier -; Cancer Epidemiology -

The news correspondents report that additional information may be obtained from T.J. Littlejohns, University of Oxford, Epidemiol Studies Unit, Nuffield Dept. of Populat Hlth, Oxford OX3 7LF, United Kingdom. Additional authors for this research include R.C. Travis, T.J. Key and N.E. Allen (see also Oncology - Prostate Cancer).

Keywords for this news article include: Oxford, United Kingdom, Europe, Prostate-Specific Antigen, Diagnostics and Screening, Prostatic Secretory Proteins, Metastatic Prostate Cancer, Prostate Specific Antigen, Biological Tumor Markers, Enzymes and Coenzymes, Risk and Prevention, Prostatic Neoplasms, Biological Factors, Peptide Hydrolases, Neoplasm Antigens, Serine Proteases, Endopeptidases, Epidemiology, Kallikreins, Immunology, Oncology, University of Oxford.

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