Newswire (Published: Tuesday, April 25, 2017, Received: Friday, April 21, 2017, 4:54:02 AM CDT)

Word Count: 397

By a News Reporter-Staff News Editor at Cancer Weekly -- Fresh data on Oncology - Prostate Cancer are presented in a new report. According to news originating from Winston Salem, North Carolina, by NewsRx correspondents, research stated, "African American men in the United States have higher incidence and mortality rates due to prostate cancer (PCa) compared to other races. In 2016 alone, nearly 30,000 cases of PCa in African American men were diagnosed and 4,450 men died from PCa."

Our news journalists obtained a quote from the research from Wake Forest University, "The underlying reasons for this health disparity in PCa are complex and include social, economic, and biologic determinants. To reduce or eliminate this health disparity, we must better understand the biology of the disease in African Americans and then develop novel diagnostic and prognostic biomarkers useful for timely and effective treatment decisions. Recently, there has been remarkable progress in understanding the role of exosomes (vesicles of 30-150 nm diameter) in cancer development and progression. Exosomes are loaded with unique cargo, including proteins, nucleic acids, lipids, and metabolites, that could predict the cells of their origin. Therefore, circulating exosomes in cancer patients are being used as a type of biopsy to identify novel biomarkers for early diagnosis, prognosis, and therapeutics."

According to the news editors, the research concluded: "In this review, we discuss the promising use of exosomes to (a) identify race-related unique biological features of PCa, and (b) discover novel biomarkers for better diagnosis and prognosis of PCa, with the goal of reducing cancer health disparities."

For more information on this research see: Exosomes-based biomarker discovery for diagnosis and prognosis of prostate cancer. Frontiers in Bioscience-Landmark, 2017;22():1682-1696. Frontiers in Bioscience-Landmark can be contacted at: Frontiers In Bioscience Inc, 16471 Scientific Way, Irvine, CA 92618, USA (see also Oncology - Prostate Cancer).

The news correspondents report that additional information may be obtained from G. Deep, Wake Forest Sch Med, Wake Forest Baptist Comprehens Canc Center, Winston Salem, NC, United States.

Keywords for this news article include: Winston Salem, North Carolina, United States, North and Central America, Cancer, Diagnostics and Screening, Cytoplasmic Structures, Prostatic Neoplasms, Transport Vesicles, Prostate Cancer, Organelles, Oncology, Genetics, Exosomes, Wake Forest University.

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