Newswire (Published: Tuesday, April 18, 2017, Received: Friday, April 14, 2017, 4:30:16 AM CDT)

Word Count: 342

By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators discuss new findings in Oncology - Prostate Cancer. According to news reporting originating in Atlanta, Georgia, by NewsRx journalists, research stated, "Prostate cancer (PCa) remains the most common cancer in American men. African-American (AA) men continue to have higher PCa prevalence and mortality rates compared to men in other populations."

The news reporters obtained a quote from the research from the Morehouse School of Medicine, "In addition to socioeconomic factors and lifestyle differences, molecular alterations contribute to this discrepancy. We summarize molecular genetics research results interrelated with the biology of PCa racial disparity. Androgen and androgen receptor (AR) pathways have long been associated with prostate growth. Racial differences have also been found among variants of genes of the enzymes involved in androgen biosynthesis and metabolism. Growth factors and their receptors are a potential cause of the disparity in PCa."

According to the news reporters, the research concluded: "Recent molecular and biotechnological approaches in the field of proteomics and genomics will greatly aid the advancement of translational research on racial disparity in PCa, which may help, in finding new prognostic markers and novel therapeutic approaches for the treatment of PCa in AA."

For more information on this research see: Molecular basis for prostate cancer racial disparities. Frontiers in Bioscience-Landmark, 2017;22():428-450. Frontiers in Bioscience-Landmark can be contacted at: Frontiers In Bioscience Inc, 16471 Scientific Way, Irvine, CA 92618, USA (see also Oncology - Prostate Cancer).

Our news correspondents report that additional information may be obtained by contacting R. Singh, Morehouse Sch Med, Dept. of Microbiol Biochem & Immunol, Atlanta, GA 30310, United States. Additional authors for this research include J.W. Lillard and R. Singh.

Keywords for this news article include: Atlanta, Georgia, United States, North and Central America, Drugs and Therapies, Prostatic Neoplasms, Prostate Cancer, Androgens, Oncology, Genetics, Morehouse School of Medicine.

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