Newswire (Published: Friday, November 17, 2017, Received: Thursday, November 9, 2017, 10:53:01 PM CST)

Word Count: 383

By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Oncology - Prostate Cancer have been presented. According to news reporting originating from Bologna, Italy, by NewsRx correspondents, research stated, "Urine may represent a convenient source of biomarkers for the early detection of Prostate Cancer (PCa) since it contains secreted prostatic products and exfoliated tumor cells. Furthermore, urine is easy to collect with non-invasive procedures which are repeatable."

Our news editors obtained a quote from the research from St. Orsola Marcello Malpighi Hospital, "Several urinary biomarkers for PCa have been proposed in the past but only one (PCA3) has been approved for clinical use and even this is not widely utilized in the routine practice. Most of these, particularly the proteins, were abandoned due to lack of confirmation. DNA markers have been proposed but they are less suitable compared to other malignancies, such as bladder cancer due to the limited amount of DNA somatic alterations in PCa compared to gene fusions and pathway activations."

According to the news editors, the research concluded: "RNA biomarkers are still the most promising and particularly miRNA and AMACR mRNA but the main weaknesses that prevented the full clinical implementation are the absence of a validated of the cut-off levels and the identification of consistent reference standards."

For more information on this research see: Urinary Biomarkers for Prostate Cancer. Current Drug Metabolism, 2017;18(8):723-726. Current Drug Metabolism can be contacted at: Bentham Science Publ Ltd, Executive Ste Y-2, PO Box 7917, Saif Zone, 1200 Br Sharjah, U Arab Emirates. (Bentham Science Publishers - www.benthamscience.com; Current Drug Metabolism - www.benthamscience.com/cdm/index.htm)

The news editors report that additional information may be obtained by contacting M. Fiorentino, St Orsola Marcello Malpighi Hosp, Pathol Department, Bologna, Italy. Additional authors for this research include C. Ciccarese, R. Montironi, M. Scarpelli, A. Lopez-Beltran, L. Cheng, H. Moch, F. Massari and F. Giunchi (see also Oncology - Prostate Cancer).

Keywords for this news article include: Bologna, Italy, Europe, Cancer, Article Review, Diagnostics and Screening, Drugs and Therapies, Prostatic Neoplasms, Prostate Cancer, Oncology, St. Orsola Marcello Malpighi Hospital.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2017, NewsRx LLC

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