Newswire (Published: Tuesday, January 24, 2017, Received: Thursday, January 19, 2017, 12:19:35 PM CST)

Word Count: 428

By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators discuss new findings in Oncology - Prostate Cancer. According to news reporting originating from Chicago, Illinois, by NewsRx correspondents, research stated, "To evaluate whether periprostatic fat volume and periprostatic fat ratio as determined by multiparametric magnetic resonance imaging (mpMRI) correlate with the presence of high-grade prostate cancer. A total of 295 consecutive patients (median age: 64, range: 38-84) underwent mpMRI of the prostate gland between August 2013 and February 2015."

Our news editors obtained a quote from the research from Rush University, "All patients underwent a 3 Tesla mpMRI. Using DynaCAD (Invivo, Gainesville, FL), we calculated the prostate volume and volume of the periprostatic fat seen on mpMRI. The periprostatic fat ratio was calculated using the formula periprostatic fat volume/prostate volume. A higher periprostatic fat volume (P <.001) and a higher periprostatic fat ratio (P <.001) were significantly associated with a higher Gleason score. Periprostatic fat ratio is a better predictor of higher Gleason score compared with periprostatic fat volume (P <.001). There was no correlation observed between periprostatic fat ratio and prostate-specific antigen (median: 7.34, range: 0.36-59.7, P = .274), age (median: 64, range: 38-84, P = .665), or body mass index (median: 28.33, range: 17.99-45.44, P = .310). Patients with a higher periprostatic fat ratio were more likely to undergo intervention for prostate cancer. A higher periprostatic fat ratio is significantly associated with a higher Gleason score."

According to the news editors, the research concluded: "Periprostatic fat ratio is a better predictor of higher Gleason score compared with periprostatic fat volume and may be an important risk factor in diagnosing patients with higher grade prostate cancer."

For more information on this research see: Periprostatic Fat: A Risk Factor for Prostate Cancer? Urology, 2016;98():107-111. Urology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Urology - www.journals.elsevier.com/urology/)

The news editors report that additional information may be obtained by contacting W.P. Tan, Rush University, Medical Center, Dept. of Urol, Chicago, IL 60612, United States. Additional authors for this research include C. Lin, M. Chen and L.A. Deane (see also Oncology - Prostate Cancer).

Keywords for this news article include: Chicago, Illinois, United States, North and Central America, Risk and Prevention, Prostatic Neoplasms, Prostate Cancer, Oncology, Rush University.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2017, NewsRx LLC

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