Newswire (Published: Tuesday, June 6, 2017, Received: Thursday, June 1, 2017, 10:43:16 PM CDT)

Word Count: 430

Data from Department of Radiology Advance Knowledge in Prostate Cancer (Role of MRI in low-risk prostate cancer: finding the wolf in sheep's clothing or the sheep in wolf's clothing?)

By a News Reporter-Staff News Editor at Cancer Weekly -- A new study on Oncology - Prostate Cancer is now available. According to news originating from Amsterdam, Netherlands, by NewsRx correspondents, research stated, "In men on active surveillance for localized prostate cancer, MRI and MRI-targeted biopsies can be used prior to confirmatory or surveillance biopsy, to detect individuals with high-grade cancer (the wolf in sheep's clothing). However, some men will have low-risk disease despite adverse MRI findings (the sheep in wolf's clothing)."

Our news journalists obtained a quote from the research from the Department of Radiology, "We review the value addition of MRI-targeted biopsies in comparison to systematic transrectal ultrasound-guided biopsies, using pathological reclassification as an end-point. At confirmatory and surveillance biopsies, both the MRI-targeted and repeat standard biopsies have shown value in identifying histologically adverse findings in men with low-risk prostate cancer. For maximal detection of clinically significant cancer, a prebiopsy MRI should be performed together with both MRItargeted and systematic transrectal ultrasound-guided biopsies. Stable disease on MRI may reduce the need for serial biopsies in some men on active surveillance. Prostate MRI and subsequent MRI-targeted biopsies are worthwhile to the current management of men with low-risk prostate cancer on active surveillance."

According to the news editors, the research concluded: "Prostate MRI, in combination with a multivariable riskprediction model may help in identifying both the wolf in sheep's clothing and the sheep in wolf's clothing, and in potentially reducing the need for serial biopsies."

For more information on this research see: Role of MRI in low-risk prostate cancer: finding the wolf in sheep's clothing or the sheep in wolf's clothing? Current Opinion in Urology, 2017;27(3):238-245. Current Opinion in Urology can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA. (Lippincott Williams and Wilkins - www.lww.com; Current Opinion in Urology - journals.lww.com/co-urology/pages/default.aspx)

The news correspondents report that additional information may be obtained from I.G. Schoots, Netherlands Canc Inst, Dept. of Radiol, Amsterdam, Netherlands. Additional authors for this research include C.M. Moore and O. Rouviere (see also Oncology - Prostate Cancer).

Keywords for this news article include: Amsterdam, Netherlands, Europe, Oncology, Article Review, Epidemiology, Prostatic Neoplasms, Prostate Cancer, Department of Radiology.

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