Newswire (Published: Tuesday, March 7, 2017, Received: Friday, March 3, 2017, 1:37:42 AM CST)

Word Count: 500

Researchers at University of Helsinki Central Hospital Have Reported New Data on Prostate Cancer (Prostate Cancer and Socioeconomic Status in the Finnish Randomized Study of Screening for Prostate Cancer)

By a News Reporter-Staff News Editor at Cancer Weekly -- Fresh data on Oncology - Prostate Cancer are presented in a new report. According to news originating from Helsinki, Finland, by NewsRx correspondents, research stated, "Prostate cancer (PC) screening remains controversial. We investigated whether screening reduces the difference in prostate cancer risk by socioeconomic status (SES)."

Our news journalists obtained a quote from the research from the University of Helsinki Central Hospital, "In 1996-2011, a total of 72,139 men from the Finnish Randomized Study of Screening for Prostate Cancer were analyzed. Outcome measures were PC incidence, mortality, and participation in screening. SES indicators were educational level, income, and home ownership status (data obtained from the Statistics Finland registry). The mean duration of follow-up was 12.7 years. Higher SES was associated with a higher incidence of low-to moderate-risk PC but with a lower risk of advanced PC. Higher education was associated with significantly lower PC mortality in both control and screening arms (risk ratio = 0.48-0.69; P< 0.05). Higher income was also associated with lower PC mortality but only in the control arm (risk ratio = 0.45-0.73; P< 0.05). There were no significant differences in SES gradient by arm (P-interaction = 0.33 and P-interaction = 0.47 for primary vs. secondary education and primary vs. tertiary education, respectively; P-interaction = 0.65 and P-interaction = 0.09 for low vs. intermediate income and low vs. high income, respectively; and P-interaction = 0.27 among home ownership status strata). Substantial gradients by SES in PC incidence and mortality were observed in the control arm. Higher SES was associated with overdiagnosis of low-risk PC and, conversely, lower risk of incurable PC and lower PC mortality."

According to the news editors, the research concluded: "Special attention should be directed toward recruiting men with low SES to participate in population-based cancer screening."

For more information on this research see: Prostate Cancer and Socioeconomic Status in the Finnish Randomized Study of Screening for Prostate Cancer. American Journal of Epidemiology, 2016;184(10):720-731. American Journal of Epidemiology can be contacted at: Oxford Univ Press Inc, Journals Dept, 2001 Evans Rd, Cary, NC 27513, USA. (Oxford University Press - www.oup.com/; American Journal of Epidemiology - aje.oxfordjournals.org)

The news correspondents report that additional information may be obtained from T.P. Kilpelainen, Helsinki Univ Hosp, FI-00029 Helsinki, Finland. Additional authors for this research include K. Talala, J. Raitanen, K. Taari, P. Kujala, T.L.J. Tammela and A. Auvinen (see also Oncology - Prostate Cancer).

Keywords for this news article include: Helsinki, Finland, Europe, Oncology, Diagnostics and Screening, Epidemiology, Metastatic Prostate Cancer, Risk and Prevention, Prostatic Neoplasms, Cancer Risk, University of Helsinki Central Hospital.

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